Coagulation Changes of Hemorrhagic Shock in Baboons
نویسندگان
چکیده
منابع مشابه
Different recovery profiles of coagulation factors, thrombin generation, and coagulation function after hemorrhagic shock in pigs.
BACKGROUND Hemorrhagic shock contributes to coagulopathy after trauma. We investigated daily changes of coagulation components and coagulation function for 5 days in hemorrhaged and resuscitated pigs. METHODS Fourteen pigs were randomized into the sham control (C) and the hemorrhage and lactated Ringer's resuscitation (H-LR) groups. On day 1, hemorrhage was induced in the H-LR group by bleedi...
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In the very beginning stage of the lung changes are Perivascular, capillary wall edema, thickening of the interstitial, lymph and vascular dilatation. In the late stage of the shock the following changes will occuree Microthromboses of the lung capillary, polynulcear infiltration into the interstitial, the existence of polynuclear in the alveoli, proliferation of interstitial mesenchyma,...
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Hemorrhagic shock is a common cause of death in emergency rooms. Current animal models of hemorrhage encounter a major problem that the volume and the rate of blood loss cannot be controlled. In addition, the use of anesthesia obscures physiological responses. Our experiments were designed to establish an animal model based on the clinical situation for studying hemorrhagic shock. Hemorrhagic s...
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HBOC-201, a bovine polymerized hemoglobin, has been proposed as a novel oxygen-carrying resuscitative fluid for patients with hemorrhagic shock (HS). Herein, we evaluated the hemostatic effects of HBOC-201 in an animal model of HS. A 40% blood loss-controlled hemorrhage and soft tissue injury were performed in 24 invasively monitored Yucatan mini-pigs. Pigs were resuscitated with HBOC-201 (HBOC...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1972
ISSN: 0003-4932
DOI: 10.1097/00000658-197202000-00007